Abstract
Eight commercially available tests for Mycoplasma pneumoniae (Serodia-Myco II, Labsystems IgM and IgG EIA, IgM and IgG LISA tests, Immuno-Well IgG test and SeroMP IgM and IgG) were compared using 204 single sera from healthy individuals. IgM peaked in late childhood and then declined, while IgG rose progressively into adulthood. Inter-assay agreement was poor. Positivity in Serodia-Myco II and LISA IgG was associated with blood group or Coombs positivity, suggesting non-specific reactions. The study confirmed that single serum serology is unsuitable for the diagnosis of M. pneumoniae infection, and that commercially available tests need further improvement.
| Original language | English |
|---|---|
| Pages (from-to) | 685-688 |
| Number of pages | 4 |
| Journal | Clinical Microbiology and Infection |
| Volume | 12 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 2006 |
| Externally published | Yes |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Assays
- Diagnosis
- IgG
- IgM
- Mycoplasma pneumoniae
- Serology
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