Evaluation of two oestrus synchronization regimens in eFSH-treated donor mares

Tal Raz; Sylvia D. Carley; Jodyne M. Green; Claire E. Card

doi:10.1016/j.tvjl.2010.03.013

Evaluation of two oestrus synchronization regimens in eFSH-treated donor mares

Tal Raz^*, Sylvia D. Carley, Jodyne M. Green, Claire E. Card

^*Corresponding author for this work

The Koret School of Veterinary Medicine

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Reliable methods for regulating oestrus and superovulation in equine embryo transfer (ET) programs are desirable. The objective in this study was to compare two oestrus synchronization methods combined with equine follicle-stimulating hormone (eFSH) treatment in an ET program. In the progesterone and estradiol-17β (P&E) group, mares (n=12) were given progesterone and estradiol-17β, daily for 10days, followed by prostaglandin (PG)F_2α on the last day. In the PG group, mares (n=12) were given PGF_2α 5days post-ovulation. In both groups donor mares were allocated to eFSH therapy, and were subsequently bred. Embryo recovery and transfer were performed routinely. The interval to ovulation (mean ± SEM, range) was not statistically different between donor mares in the P&E group (10.2 ± 0.3, 9-12. days) and donor mares in the PG group (8.7 ± 0.7, 4-12. days). Among donor mares, the synchrony of ovulations was higher following the P&E regimen (P< 0.05); however, there was a tendency (P< 0.06) for fewer ovulations than in the PG group (1.5 ± 0.3 vs. 2.5 ± 0.4 ovulations, respectively). Embryo recovery (0.9 ± 0.3 vs. 1.4 ± 0.3 embryo/recovery) and recipient pregnancy rate per transferred embryo (4/9, 44% vs. 4/15, 27%) were similar. It was concluded that the P&E regimen was more reliable for synchronization of oestrus in eFSH-treated mares but the fewer ovulations may curtail any advantage of this regimen.

Original language	English
Pages (from-to)	105-109
Number of pages	5
Journal	Veterinary Journal
Volume	188
Issue number	1
DOIs	https://doi.org/10.1016/j.tvjl.2010.03.013
State	Published - Apr 2011

Bibliographical note

Funding Information:
The authors gratefully acknowledge the Alberta Agriculture Research Institute and the Calgary Stampede Corporation, Calgary, Alberta, for financial support and use of their horses.

Keywords

EFSH
Embryo transfer
Mare
Oestrus synchronization
Superovulation

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10.1016/j.tvjl.2010.03.013

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title = "Evaluation of two oestrus synchronization regimens in eFSH-treated donor mares",

abstract = "Reliable methods for regulating oestrus and superovulation in equine embryo transfer (ET) programs are desirable. The objective in this study was to compare two oestrus synchronization methods combined with equine follicle-stimulating hormone (eFSH) treatment in an ET program. In the progesterone and estradiol-17β (P&E) group, mares (n=12) were given progesterone and estradiol-17β, daily for 10days, followed by prostaglandin (PG)F2α on the last day. In the PG group, mares (n=12) were given PGF2α 5days post-ovulation. In both groups donor mares were allocated to eFSH therapy, and were subsequently bred. Embryo recovery and transfer were performed routinely. The interval to ovulation (mean ± SEM, range) was not statistically different between donor mares in the P&E group (10.2 ± 0.3, 9-12. days) and donor mares in the PG group (8.7 ± 0.7, 4-12. days). Among donor mares, the synchrony of ovulations was higher following the P&E regimen (P< 0.05); however, there was a tendency (P< 0.06) for fewer ovulations than in the PG group (1.5 ± 0.3 vs. 2.5 ± 0.4 ovulations, respectively). Embryo recovery (0.9 ± 0.3 vs. 1.4 ± 0.3 embryo/recovery) and recipient pregnancy rate per transferred embryo (4/9, 44% vs. 4/15, 27%) were similar. It was concluded that the P&E regimen was more reliable for synchronization of oestrus in eFSH-treated mares but the fewer ovulations may curtail any advantage of this regimen.",

keywords = "EFSH, Embryo transfer, Mare, Oestrus synchronization, Superovulation",

author = "Tal Raz and Carley, {Sylvia D.} and Green, {Jodyne M.} and Card, {Claire E.}",

note = "Funding Information: The authors gratefully acknowledge the Alberta Agriculture Research Institute and the Calgary Stampede Corporation, Calgary, Alberta, for financial support and use of their horses.",

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AU - Carley, Sylvia D.

AU - Green, Jodyne M.

AU - Card, Claire E.

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AB - Reliable methods for regulating oestrus and superovulation in equine embryo transfer (ET) programs are desirable. The objective in this study was to compare two oestrus synchronization methods combined with equine follicle-stimulating hormone (eFSH) treatment in an ET program. In the progesterone and estradiol-17β (P&E) group, mares (n=12) were given progesterone and estradiol-17β, daily for 10days, followed by prostaglandin (PG)F2α on the last day. In the PG group, mares (n=12) were given PGF2α 5days post-ovulation. In both groups donor mares were allocated to eFSH therapy, and were subsequently bred. Embryo recovery and transfer were performed routinely. The interval to ovulation (mean ± SEM, range) was not statistically different between donor mares in the P&E group (10.2 ± 0.3, 9-12. days) and donor mares in the PG group (8.7 ± 0.7, 4-12. days). Among donor mares, the synchrony of ovulations was higher following the P&E regimen (P< 0.05); however, there was a tendency (P< 0.06) for fewer ovulations than in the PG group (1.5 ± 0.3 vs. 2.5 ± 0.4 ovulations, respectively). Embryo recovery (0.9 ± 0.3 vs. 1.4 ± 0.3 embryo/recovery) and recipient pregnancy rate per transferred embryo (4/9, 44% vs. 4/15, 27%) were similar. It was concluded that the P&E regimen was more reliable for synchronization of oestrus in eFSH-treated mares but the fewer ovulations may curtail any advantage of this regimen.

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Evaluation of two oestrus synchronization regimens in eFSH-treated donor mares

Abstract

Bibliographical note

Keywords

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