Evolution of substrate specificity in a recipient's enzyme following horizontal gene transfer

Keyphrases

• Substrate Specificity 100%
• Horizontal Gene Transfer 100%
• PriA 80%
• TrpF 60%
• Isomerase 40%
• Histidine 40%
• Mycobacterium 40%
• Corynebacterium 40%
• Amino Acids 20%
• Gain-of-function 20%
• Metabolism 20%
• Operon 20%
• Enzyme Function 20%
• Phylogenetic Reconstruction 20%
• Dual Substrate 20%
• Tryptophan 20%
• Actinobacteria 20%
• Conformational States 20%
• X-ray Crystallography 20%
• Histidine Biosynthesis 20%
• Specialized Functions 20%
• Comparative Genomics 20%
• Molecular Dynamics Analysis 20%
• In Vitro Release Kinetics 20%
• Ancestral Proteins 20%
• Enzyme Kinetic Analysis 20%
• Comparative Phylogenetics 20%
• Bacterial Metabolism 20%
• In Silico 20%
• Active Site mutant 20%
• Enzyme Evolution 20%

Biochemistry, Genetics and Molecular Biology

• Enzyme 100%
• Enzyme Specificity 100%
• Horizontal Gene Transfer 100%
• Anabolism 40%
• Isomerase 40%
• Mycobacteria 40%
• Corynebacterium 40%
• Histidine 40%
• Amino Acids 20%
• Active Site 20%
• Metabolic Pathway 20%
• Operon 20%
• Phylogeny 20%
• Reconstruction 20%
• Actinobacteria 20%
• Kinetics 20%
• X-Ray Crystallography 20%
• Enzyme Kinetics 20%
• Bacterial Metabolism 20%
• Comparative Genomics 20%
• Cladistics 20%
• Tryptophan 20%

Immunology and Microbiology

• Enzyme Specificity 100%
• Horizontal Gene Transfer 100%
• Corynebacterium 40%
• Mycobacteria 40%
• Kinetics 20%
• Phylogeny 20%
• Actinobacteria 20%
• Operon 20%
• X Ray 20%
• Bacterial Metabolism 20%
• Enzyme Kinetics 20%
• Cladistics 20%