Evolutionary dynamics of endogenous feline leukemia virus proliferation among species of the domestic cat lineage

Sagi Polani; Alfred L. Roca; Bryan B. Rosensteel; Sergios Orestis Kolokotronis; Gila Kahila Bar-Gal

doi:10.1016/j.virol.2010.06.010

Evolutionary dynamics of endogenous feline leukemia virus proliferation among species of the domestic cat lineage

Sagi Polani, Alfred L. Roca^*, Bryan B. Rosensteel, Sergios Orestis Kolokotronis, Gila Kahila Bar-Gal

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

Endogenous feline leukemia viruses (enFeLVs) occur in the germ lines of the domestic cat and related wild species (genus Felis). We sequenced the long terminal repeats and part of the env region of enFeLVs in domestic cats and five wild species. A total of 305 enFeLV sequences were generated across 17 individuals, demonstrating considerable diversity within two major clades. Distinct proliferations of enFeLVs occurred before and after the black-footed cat diverged from the other species. Diversity of enFeLVs was limited for the sand cat and jungle cat suggesting that proliferation of enFeLVs occurred within these species after they diverged. Relationships among enFeLVs were congruent with host species relationships except for the jungle cat, which carried only enFeLVs from a lineage that recently invaded the germline (enFeLV-AGTT). Comparison of wildcat and domestic cat enFeLVs indicated that a distinctive germ line invasion of enFeLVs has not occurred since the cat was domesticated.

Original language	English
Pages (from-to)	397-407
Number of pages	11
Journal	Virology
Volume	405
Issue number	2
DOIs	https://doi.org/10.1016/j.virol.2010.06.010
State	Published - 30 Sep 2010

Bibliographical note

Funding Information:
We thank S. J. O'Brien and the LGD/NCI for initial access to samples. All samples had been collected in compliance with federal regulations and permits. This work was supported by the Morris Animal Foundation grant D06FE-029 . SOK was supported by the U.S. Defense Advanced Research Projects Agency (DARPA) .

Keywords

African wildcat
Black-footed cat
Domestic cat
Endogenous retroviruses
European wildcat
Jungle cat
Oncoretroviruses
Sand cat

Access to Document

10.1016/j.virol.2010.06.010

Cite this

@article{861b439831d44212976911c13072bb2f,

title = "Evolutionary dynamics of endogenous feline leukemia virus proliferation among species of the domestic cat lineage",

abstract = "Endogenous feline leukemia viruses (enFeLVs) occur in the germ lines of the domestic cat and related wild species (genus Felis). We sequenced the long terminal repeats and part of the env region of enFeLVs in domestic cats and five wild species. A total of 305 enFeLV sequences were generated across 17 individuals, demonstrating considerable diversity within two major clades. Distinct proliferations of enFeLVs occurred before and after the black-footed cat diverged from the other species. Diversity of enFeLVs was limited for the sand cat and jungle cat suggesting that proliferation of enFeLVs occurred within these species after they diverged. Relationships among enFeLVs were congruent with host species relationships except for the jungle cat, which carried only enFeLVs from a lineage that recently invaded the germline (enFeLV-AGTT). Comparison of wildcat and domestic cat enFeLVs indicated that a distinctive germ line invasion of enFeLVs has not occurred since the cat was domesticated.",

keywords = "African wildcat, Black-footed cat, Domestic cat, Endogenous retroviruses, European wildcat, Jungle cat, Oncoretroviruses, Sand cat",

author = "Sagi Polani and Roca, {Alfred L.} and Rosensteel, {Bryan B.} and Kolokotronis, {Sergios Orestis} and Bar-Gal, {Gila Kahila}",

note = "Funding Information: We thank S. J. O'Brien and the LGD/NCI for initial access to samples. All samples had been collected in compliance with federal regulations and permits. This work was supported by the Morris Animal Foundation grant D06FE-029 . SOK was supported by the U.S. Defense Advanced Research Projects Agency (DARPA) .",

year = "2010",

month = sep,

day = "30",

doi = "10.1016/j.virol.2010.06.010",

language = "אנגלית",

volume = "405",

pages = "397--407",

journal = "Virology",

issn = "0042-6822",

publisher = "Academic Press Inc.",

number = "2",

}

TY - JOUR

T1 - Evolutionary dynamics of endogenous feline leukemia virus proliferation among species of the domestic cat lineage

AU - Polani, Sagi

AU - Roca, Alfred L.

AU - Rosensteel, Bryan B.

AU - Kolokotronis, Sergios Orestis

AU - Bar-Gal, Gila Kahila

N1 - Funding Information: We thank S. J. O'Brien and the LGD/NCI for initial access to samples. All samples had been collected in compliance with federal regulations and permits. This work was supported by the Morris Animal Foundation grant D06FE-029 . SOK was supported by the U.S. Defense Advanced Research Projects Agency (DARPA) .

PY - 2010/9/30

Y1 - 2010/9/30

N2 - Endogenous feline leukemia viruses (enFeLVs) occur in the germ lines of the domestic cat and related wild species (genus Felis). We sequenced the long terminal repeats and part of the env region of enFeLVs in domestic cats and five wild species. A total of 305 enFeLV sequences were generated across 17 individuals, demonstrating considerable diversity within two major clades. Distinct proliferations of enFeLVs occurred before and after the black-footed cat diverged from the other species. Diversity of enFeLVs was limited for the sand cat and jungle cat suggesting that proliferation of enFeLVs occurred within these species after they diverged. Relationships among enFeLVs were congruent with host species relationships except for the jungle cat, which carried only enFeLVs from a lineage that recently invaded the germline (enFeLV-AGTT). Comparison of wildcat and domestic cat enFeLVs indicated that a distinctive germ line invasion of enFeLVs has not occurred since the cat was domesticated.

AB - Endogenous feline leukemia viruses (enFeLVs) occur in the germ lines of the domestic cat and related wild species (genus Felis). We sequenced the long terminal repeats and part of the env region of enFeLVs in domestic cats and five wild species. A total of 305 enFeLV sequences were generated across 17 individuals, demonstrating considerable diversity within two major clades. Distinct proliferations of enFeLVs occurred before and after the black-footed cat diverged from the other species. Diversity of enFeLVs was limited for the sand cat and jungle cat suggesting that proliferation of enFeLVs occurred within these species after they diverged. Relationships among enFeLVs were congruent with host species relationships except for the jungle cat, which carried only enFeLVs from a lineage that recently invaded the germline (enFeLV-AGTT). Comparison of wildcat and domestic cat enFeLVs indicated that a distinctive germ line invasion of enFeLVs has not occurred since the cat was domesticated.

KW - African wildcat

KW - Black-footed cat

KW - Domestic cat

KW - Endogenous retroviruses

KW - European wildcat

KW - Jungle cat

KW - Oncoretroviruses

KW - Sand cat

UR - http://www.scopus.com/inward/record.url?scp=77955658684&partnerID=8YFLogxK

U2 - 10.1016/j.virol.2010.06.010

DO - 10.1016/j.virol.2010.06.010

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 20615520

AN - SCOPUS:77955658684

SN - 0042-6822

VL - 405

SP - 397

EP - 407

JO - Virology

JF - Virology

IS - 2

ER -

Evolutionary dynamics of endogenous feline leukemia virus proliferation among species of the domestic cat lineage

Abstract

Bibliographical note

Keywords

Access to Document

Other files and links

Fingerprint

Cite this