Exceptional oral manifestations of amyloid light chain protein (AL) systemic amyloidosis

Sharon Elad*, Rakefet Czerninski, Stuart Fischman, Na'Ama Keshet, Scott Drucker, Tzipporah Davidovich, Neta Goldschmidt

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    23 Scopus citations


    Oral amyloidosis is usually presented in the tongue and is often associated with multiple myeloma. We present three patients with unusual oral manifestations of primary amyloidosis, which to the best of our knowledge have not been previously published. In two cases the oral manifestation was overt at the time of diagnosis and all cases ended in patient mortality. Since these oral manifestations can contribute to the diagnosis of systemic amyloidosis, clinicians should be made aware of them. Future research should assess the significance of oral manifestation as a prognostic indicator.

    Original languageAmerican English
    Pages (from-to)27-31
    Number of pages5
    JournalAmyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis
    Issue number1
    StatePublished - Mar 2010


    • Air obstruction
    • Bleeding
    • Haematoma
    • Macroglossia
    • Multiple myeloma
    • Oral
    • Orange
    • Suffocation
    • Systemic amyloidosis


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