Exercise of heat-exposed rats prevents myocardial pathology

R. Yarom*, E. Levy, M. Horowitz

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

1. 1.|Light and electron microscope morphometry has been used to study the effect on heart morphology of a sedentary life style in normothermic (24°C) and warm acclimated (34°C) rats in comparison with exercised normothermic and warm acclimated rats. 2. 2.|The sedentary acclimated rats had multiple foci of myocardial necrosis while the exercised rats did not. The capillary to myofibre ratio and the number of mast cells were higher in the acclimated exercised hearts than in hearts from all the other groups. The intercapillary distance and the mitochondrial volume fractions were not affected by any treatment regime. 3. 3.|It is concluded that although some neoangiogenesis occurs during exercise + heat, the neoangiogenesis does not explain the absence of myocardial pathology produced by heat alone.

Original languageEnglish
Pages (from-to)159-163
Number of pages5
JournalJournal of Thermal Biology
Volume18
Issue number3
DOIs
StatePublished - Jun 1993

Keywords

  • acclimation
  • angiogenesis
  • cardiac morphometry
  • cardioprotection
  • Exercise
  • rat

Fingerprint

Dive into the research topics of 'Exercise of heat-exposed rats prevents myocardial pathology'. Together they form a unique fingerprint.

Cite this