Experimental surgical treatment for recurrent epistaxis

Purpose: To evaluate a new technique of submucosal supraperichondrial (SMSP) dissection of the nasal septum and its subsequent effect on the vascularity of the mucosa. A reduction may decrease the rate of recurrent anterior epistaxis. Materials and Methods: The procedure was performed on one side of the nasal septum of 16 laboratory rabbits. After healing occurred 3 months later, the animals' septa were excised and stained. Both sides were then compared by using standardized microscopic field analysis. Results: The reduction in both the number of blood vessels on the operated side of the septum and the proportion of area occupied by these vessels was statistically significant (P < .004). Conclusion: This technique led to a reduction in the vascularity of the nasal septal mucosa, 3 months after dissection was performed. Healing, which occurs by a process of fibrosis, yielded a less vascularized tissue. Although further laboratory and clinical assessment is recommended, this technique may prove valuable in reducing the rate of recurrent anterior epistaxis.