Exploring models of the influenza A M2 channel: MD simulations in a phospholipid bilayer

Keyphrases

• Amantadine 33%
• Antiviral Drugs 33%
• Aspartate 33%
• Breathing Motion 33%
• Channel Shape 33%
• Channel System 33%
• Closed Channel 33%
• Complex Channel 33%
• Dimer Structure 33%
• Electrostatic Calculations 33%
• Four-helix Bundle 33%
• Glycerol 33%
• Helix 66%
• Helix Bundle 100%
• Influenza A M2 100%
• Influenza Virus 33%
• Ion Channel Activity 33%
• Ion Channels 33%
• Ionizable 33%
• Leucine 33%
• M2 Protein 33%
• M2 Proton Channel 100%
• Molecular Dynamics Simulation 100%
• Nanosecond Time Scale 33%
• Native Varieties 33%
• Palmitoyl-CoA 33%
• Phosphatidylcholine Bilayers 33%
• Phospholipid Bilayer 100%
• Proton 33%
• Proton Channel 33%
• Restricted Motion 33%
• Selective Channels 33%
• Small Ions 33%
• Starting Model 33%
• State of Charge 33%
• Transmembrane 33%
• Trapped Water 33%

Biochemistry, Genetics and Molecular Biology

• Amantadine 25%
• Aspartic Acid 25%
• C-Terminus 25%
• Exhalation 25%
• Glycerol 25%
• Helix Bundle 100%
• Influenza A Virus 25%
• Ion Channel 50%
• Lecithin 25%
• Leucine 25%
• Motion 50%
• N-Terminus 25%
• Phospholipid Bilayer 100%
• Serine 25%
• Static Electricity 25%
• Virus Forms 25%