TY - JOUR
T1 - Extensions of the Melander–Westheimer Postulate
T2 - Isotope Effects in Reactions with Equilibrium Values Far from Unity
AU - Agmon, Noam
PY - 1985
Y1 - 1985
N2 - The symmetric dependence of experimental primary kinetic isotope effects on the free energy change, obtained for reaction series with zero equilibrium isotope effects, can be inverted to obtain the free energy profile along the reaction coordinate. Trends in the kinetic isotope effects for the general case of non‐vanishing equilibrium effects can be understood by an extension of the same theory. Comparison is made with experiments for reactions of halogen atoms with hydrogen/deuterium molecules.
AB - The symmetric dependence of experimental primary kinetic isotope effects on the free energy change, obtained for reaction series with zero equilibrium isotope effects, can be inverted to obtain the free energy profile along the reaction coordinate. Trends in the kinetic isotope effects for the general case of non‐vanishing equilibrium effects can be understood by an extension of the same theory. Comparison is made with experiments for reactions of halogen atoms with hydrogen/deuterium molecules.
UR - http://www.scopus.com/inward/record.url?scp=84985089422&partnerID=8YFLogxK
U2 - 10.1002/ijch.198500122
DO - 10.1002/ijch.198500122
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AN - SCOPUS:84985089422
SN - 0021-2148
VL - 26
SP - 375
EP - 377
JO - Israel Journal of Chemistry
JF - Israel Journal of Chemistry
IS - 4
ER -