TY - JOUR
T1 - Fetal cardiac ventricular volume, cardiac output, and ejection fraction determined with 4-dimensional ultrasound using spatiotemporal image correlation and virtual organ computer-aided analysis
AU - Hamill, Neil
AU - Yeo, Lami
AU - Romero, Roberto
AU - Hassan, Sonia S.
AU - Myers, Stephen A.
AU - Mittal, Pooja
AU - Kusanovic, Juan Pedro
AU - Balasubramaniam, Mamtha
AU - Chaiworapongsa, Tinnakorn
AU - Vaisbuch, Edi
AU - Espinoza, Jimmy
AU - Gotsch, Francesca
AU - Goncalves, Luis F.
AU - Lee, Wesley
PY - 2011/7
Y1 - 2011/7
N2 - Objective: The objective of this study was to quantify fetal cardiovascular parameters using spatiotemporal image correlation (STIC) and virtual organ computer-aided analysis (VOCAL). Study Design: A cross-sectional study was performed in normal pregnancies (19-42 weeks) to evaluate ventricular volume, stroke volume (SV), cardiac output (CO), and ejection fraction (EF). The CO was also expressed as a function of estimated fetal weight and biometric parameters. Results: The following results were found: (1) 184 STIC datasets; (2) with advancing gestation, ventricular volume, SV, CO, and adjusted CO increased, whereas EF decreased; (3) right ventricular (RV) volume was larger than the left ventricular (LV) volume in systole (0.50 vs 0.27 mL; P < .001) and diastole (1.20 vs 1.03 mL; P < .001); (4) there were no differences between the LV and RV in SV, CO, or adjusted CO; and (5) LV EF was greater than the RV EF (72.2 vs 62.4%; P < .001). Conclusion: Normal fetal cardiovascular physiology is characterized by a larger RV volume and a greater LV EF, resulting in similar LV and RV SV and CO.
AB - Objective: The objective of this study was to quantify fetal cardiovascular parameters using spatiotemporal image correlation (STIC) and virtual organ computer-aided analysis (VOCAL). Study Design: A cross-sectional study was performed in normal pregnancies (19-42 weeks) to evaluate ventricular volume, stroke volume (SV), cardiac output (CO), and ejection fraction (EF). The CO was also expressed as a function of estimated fetal weight and biometric parameters. Results: The following results were found: (1) 184 STIC datasets; (2) with advancing gestation, ventricular volume, SV, CO, and adjusted CO increased, whereas EF decreased; (3) right ventricular (RV) volume was larger than the left ventricular (LV) volume in systole (0.50 vs 0.27 mL; P < .001) and diastole (1.20 vs 1.03 mL; P < .001); (4) there were no differences between the LV and RV in SV, CO, or adjusted CO; and (5) LV EF was greater than the RV EF (72.2 vs 62.4%; P < .001). Conclusion: Normal fetal cardiovascular physiology is characterized by a larger RV volume and a greater LV EF, resulting in similar LV and RV SV and CO.
KW - 3-dimensional
KW - 4-dimensional
KW - contour finder
KW - fetal echocardiography
KW - fetus
KW - prenatal diagnosis
KW - sonography
KW - spatiotemporal image correlation
KW - STIC
KW - stroke volume
KW - ultrasound
KW - virtual organ computer-aided analysis
KW - VOCAL
UR - http://www.scopus.com/inward/record.url?scp=79959691125&partnerID=8YFLogxK
U2 - 10.1016/j.ajog.2011.02.028
DO - 10.1016/j.ajog.2011.02.028
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AN - SCOPUS:79959691125
SN - 0002-9378
VL - 205
SP - 76.e1-76.e10
JO - American Journal of Obstetrics and Gynecology
JF - American Journal of Obstetrics and Gynecology
IS - 1
ER -