Abstract
The fluorescence depolarization associated with the hydrophobic fluorescent probe 1,6-diphenyl-1,3,5-hexatriene is used to monitor the changes in fluidity accompanying the gel-liquid crystalline phase transition in synthetic phosphatidylcholine dispersions. The parameters of the phase transition are determined for both large, multilamellar liposomes and small, single-lamellar vesicles. These parameters are compared with those obtained using other techniques. In addition, the data are interpreted in terms of two limiting molecular models, which in turn offer insight into the structural differences between multilamellar liposomes and small vesicles.
Original language | English |
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Pages (from-to) | 4521-4528 |
Number of pages | 8 |
Journal | Biochemistry |
Volume | 15 |
Issue number | 20 |
DOIs | |
State | Published - 1 Oct 1976 |
Externally published | Yes |