Following a protein kinase activity using a field-effect transistor device

Ronit Freeman; Ron Gill; Itamar Willner

doi:10.1039/b707677k

Following a protein kinase activity using a field-effect transistor device

Ronit Freeman, Ron Gill, Itamar Willner^*

^*Corresponding author for this work

Institute of Chemistry

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

The specific phosphorylation of a peptide-functionalized ion-sensitive field-effect transistor device by casein kinase II in the presence of ATP enables the electronic readout of the protein kinase activity; treatment of the phosphorylated surface with alkaline phosphatase results in the regeneration of the active sensing surface.

Original language	English
Pages (from-to)	3450-3452
Number of pages	3
Journal	Chemical Communications
Issue number	33
DOIs	https://doi.org/10.1039/b707677k
State	Published - 2007

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title = "Following a protein kinase activity using a field-effect transistor device",

abstract = "The specific phosphorylation of a peptide-functionalized ion-sensitive field-effect transistor device by casein kinase II in the presence of ATP enables the electronic readout of the protein kinase activity; treatment of the phosphorylated surface with alkaline phosphatase results in the regeneration of the active sensing surface.",

author = "Ronit Freeman and Ron Gill and Itamar Willner",

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Following a protein kinase activity using a field-effect transistor device

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