Following a protein kinase activity using a field-effect transistor device

Ronit Freeman; Ron Gill; Itamar Willner

doi:10.1039/b707677k

Following a protein kinase activity using a field-effect transistor device

Ronit Freeman
, Ron Gill
, Itamar Willner^*

^*Corresponding author for this work

Institute of Chemistry

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

The specific phosphorylation of a peptide-functionalized ion-sensitive field-effect transistor device by casein kinase II in the presence of ATP enables the electronic readout of the protein kinase activity; treatment of the phosphorylated surface with alkaline phosphatase results in the regeneration of the active sensing surface.

Original language	English
Pages (from-to)	3450-3452
Number of pages	3
Journal	Chemical Communications
Issue number	33
DOIs	https://doi.org/10.1039/b707677k
State	Published - 2007

Access to Document

10.1039/b707677k

Cite this

@article{62870fa19c574cd4b668c665bb556ea5,

title = "Following a protein kinase activity using a field-effect transistor device",

abstract = "The specific phosphorylation of a peptide-functionalized ion-sensitive field-effect transistor device by casein kinase II in the presence of ATP enables the electronic readout of the protein kinase activity; treatment of the phosphorylated surface with alkaline phosphatase results in the regeneration of the active sensing surface.",

author = "Ronit Freeman and Ron Gill and Itamar Willner",

year = "2007",

doi = "10.1039/b707677k",

language = "אנגלית",

pages = "3450--3452",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "33",

}

TY - JOUR

T1 - Following a protein kinase activity using a field-effect transistor device

AU - Freeman, Ronit

AU - Gill, Ron

AU - Willner, Itamar

PY - 2007

Y1 - 2007

N2 - The specific phosphorylation of a peptide-functionalized ion-sensitive field-effect transistor device by casein kinase II in the presence of ATP enables the electronic readout of the protein kinase activity; treatment of the phosphorylated surface with alkaline phosphatase results in the regeneration of the active sensing surface.

AB - The specific phosphorylation of a peptide-functionalized ion-sensitive field-effect transistor device by casein kinase II in the presence of ATP enables the electronic readout of the protein kinase activity; treatment of the phosphorylated surface with alkaline phosphatase results in the regeneration of the active sensing surface.

UR - https://www.scopus.com/pages/publications/34548046991

U2 - 10.1039/b707677k

DO - 10.1039/b707677k

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 17700878

AN - SCOPUS:34548046991

SN - 1359-7345

SP - 3450

EP - 3452

JO - Chemical Communications

JF - Chemical Communications

IS - 33

ER -

Following a protein kinase activity using a field-effect transistor device

Abstract

Access to Document

Other files and links

Fingerprint

Cite this