Abstract
The MRC Centre for Protein Engineering (CPE) hosted and trained many scientists over the years. It is a unique research environment that shaped the career of many scientists in all aspects. These include research directions and methodologies, but even more important - issues such as how to approach scientific problems and how to manage a research team. Alan Fersht was the director of the CPE when I joined it as a postdoc in the year 2000. In the current article for the PEDS special CPE issue, I will review how my scientific research and my approach to science developed from the days I arrived to the CPE as a young peptide chemist and throughout the years I spent at the CPE, and how it shaped my current research interests and attitude. I will focus on two major fields: (i) Using peptides to study and modulate the structure and interactions of proteins; (ii) Using quantitative biophysical methods to study proteins and their interactions at the molecular level. The Author 2010. Published by Oxford University Press.
| Original language | English |
|---|---|
| Pages (from-to) | 241-245 |
| Number of pages | 5 |
| Journal | Protein Engineering, Design and Selection |
| Volume | 24 |
| Issue number | 1-2 |
| DOIs | |
| State | Published - Jan 2011 |
Bibliographical note
Funding Information:A.F. was supported during his post-doc at the CPE by a long-term fellowship from the Human Frontier Science Program Organization. A.F. is currently supported by a starting grant from the European Research Council under the European Community’s Seventh Framework Programme (FP7/2007-2013)/ERC Grant agreement n° 203413.
Keywords
- biophysics
- peptides
- protein engineering
- protein-protein interactions
- proteins