From phosphonates to catalytic antibodies. a novel route to phosphonoester transition state analogs and haptens

Bernard S. Green, Zelig Eshhar

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

We present here a newly developed approach based on DBU catalyzed transesterification of bis-PNP-phosphonates, used for the preparation of phosphonoesters and their protein conjugates. These are being used, as transition state analogs, to elicit catalytic antibodies having enzyme-like properties.

Original languageEnglish
Pages (from-to)123-126
Number of pages4
JournalPhosphorus, Sulfur and Silicon and the Related Elements
Volume76
Issue number1-4
DOIs
StatePublished - 1 Mar 1993

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