Fumarase: A mitochondrial metabolic enzyme and a cytosolic/nuclear component of the dna damage response

Keyphrases

• DNA Damage Response 100%
• Metabolic Enzymes 100%
• Fumarase 100%
• Nuclear Components 100%
• Hypoxia-inducible Factor 30%
• Tumor Suppressor 20%
• Fumaric Acid 20%
• Hereditary Leiomyomatosis 20%
• Renal Cancer 20%
• Transcription Factor 10%
• DNA Damage 10%
• Metabolic Control 10%
• Enzymatic Activity 10%
• Mitochondria 10%
• Fumarate 10%
• High Concentration 10%
• DNA Double-strand Breaks 10%
• Eukaryotes 10%
• Angiogenesis 10%
• Proteasomal Degradation 10%
• Tumorigenesis 10%
• Human Cells 10%
• Mitochondrial Matrix 10%
• Isoenzymes 10%
• Regulated Genes 10%
• Cancer Tumor 10%
• Yeast Strains 10%
• Tricarboxylic Acid Cycle Enzymes 10%
• Tumor Propagation 10%
• Primary Metabolism 10%
• Tumor Susceptibility 10%
• Competitive Inhibitor 10%
• Hypoxia-inducible Factor Prolyl Hydroxylase 10%
• DNA Damage Induction 10%
• Microvessel Density 10%
• Biallelic mutations 10%

Biochemistry, Genetics and Molecular Biology

• Enzyme 100%
• Fumarase 100%
• Hypoxia-Inducible Factors 40%
• DNA Damage Response 30%
• DNA Damage 20%
• Tumor Suppressor Protein 20%
• Cancer Cell 20%
• Fumaric Acid 20%
• Transcription Factors 10%
• Metabolic Regulation 10%
• Metabolic Pathway 10%
• Enzyme Activity 10%
• Mitochondrion 10%
• Vascular Endothelial Growth Factor 10%
• Carcinogenesis 10%
• Angiogenesis 10%
• Mitochondrial Matrix 10%
• Citric Acid Cycle 10%
• Eukaryote 10%
• Isoenzyme 10%
• Procollagen-Proline Dioxygenase 10%
• Competitive Inhibition 10%