Functional biosensor systems via surface-nanoengineering of electronic elements

Itamar Willner*, Bilha Willner, Eugenii Katz

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

Bioelectronics is a progressing interdisciplinary research field that involves the integration of biomaterials with electronic transducers such as electrodes, field-effect transistors or piezoelectric crystals. Surface engineering of biomaterials such as enzymes, antigen-antibodies or DNA on the electronic supports controls the electrical properties of the biomaterial/transducer interface and enables the electronic transduction of biorecognition events, or biocatalyzed transformation, on the transducers. The development of biosensor systems of tailored sensitivites and specificities represents a major advance in bioelectronics.

Original languageEnglish
Pages (from-to)325-355
Number of pages31
JournalReviews in Molecular Biotechnology
Volume82
Issue number4
DOIs
StatePublished - 2002

Keywords

  • Antigen-antibody
  • Bioelectronics
  • Biosensors
  • DNA-sensors
  • Enzyme-electrodes

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