Gem -Diborylalkanes: Recent advances in their preparation, transformation and application

Rajender Nallagonda, Kishor Padala, Ahmad Masarwa*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

144 Scopus citations

Abstract

Recently, gem-diborylalkanes have attracted much attention as versatile building blocks and fundamental intermediates in organic synthesis, because they enable multiple C-C bond construction and further transformation at C-B bonds. Importantly, gem-diborylalkanes can be utilised as bisnucleophilic partners in a variety of chemo-selective C-C bond-forming reactions. This review describes recent developments in synthesising gem-diborylalkanes in complex molecules along with their chemical transformation. In the first part of the review the different synthetic approaches used to synthesise gem-diborylalkanes are described. In the second part, an overview of the chemoselective transformation of gem-diborylalkanes into various functionalized materials is discussed along with one-carbon homologation of diborylmethane via a selective uni- and bidirectional method.

Original languageAmerican English
Pages (from-to)1050-1064
Number of pages15
JournalOrganic and Biomolecular Chemistry
Volume16
Issue number7
DOIs
StatePublished - 2018

Bibliographical note

Publisher Copyright:
© The Royal Society of Chemistry 2018.

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