Gene augmentation therapy attenuates retinal degeneration in a knockout mouse model of Fam161a retinitis pigmentosa

Keyphrases

• Knock-in Mouse Model 100%
• Retinitis pigmentosa 100%
• Retinal Degeneration 100%
• Gene Augmentation Therapy 100%
• FAM161A 100%
• Photoreceptor 66%
• Inherited Retinal Disease 66%
• Gene Therapy 33%
• Novel Therapeutics 33%
• Cell-based 33%
• Retinal Function 33%
• Adenovirus 33%
• Rescue Effect 33%
• Optical Coherence Tomography 33%
• Biallelic 33%
• Photoreceptor Degeneration 33%
• Full-field Electroretinography 33%
• In Vivo Assessment 33%
• Immunohistochemical Study 33%
• Retinal Structure 33%
• Subretinal Space 33%
• Age-related Macular Degeneration 33%
• Accessible Treatment 33%
• Fundus Autofluorescence 33%
• Photoreceptor Cell Death 33%
• Optomotor Response 33%
• Quantitative Histology 33%
• Functional Rescue 33%
• Pathogenic Variants 33%
• Response Test 33%
• Histology Study 33%

Medicine and Dentistry

• Retinitis pigmentosa 100%
• Retina Degeneration 100%
• Photoreceptor 100%
• Knockout Mouse 100%
• Retina Disease 66%
• Ex Vivo 33%
• Electroretinography 33%
• Cell Death 33%
• Autofluorescence 33%
• Cell Therapy 33%
• Optical Coherence Tomography 33%
• Therapeutic Modality 33%
• Age Related Macular Degeneration 33%
• Adeno-Associated Virus 33%
• Cell Degeneration 33%
• Diseases 33%
• Histology 33%

Neuroscience

• Photoreceptor 100%
• Retinitis pigmentosa 100%
• Retinal Degeneration 100%
• Retinal Disease 66%
• In Vivo 33%
• Cell Death 33%
• Electroretinography 33%
• Cell Therapy 33%
• Age-Related Macular Degeneration 33%
• Adeno-Associated Virus 33%
• Cell Degeneration 33%
• Histology 33%
• Autofluorescence 33%
• Optomotor Response 33%