The vast majority of genetic studies of phlebotomine sandflies have had as their goal the resolution of taxonomic problems. In this paper, Gregory Lanzaro and Alon Warburg summarize the literature describing levels of genetic polymorphism, both within and between sandfly species, and speculate on the significance of variability in the vector to the complex epidemiology of leishmaniasis.
Bibliographical noteFunding Information:
Thusw orkw ass upported by grant ID-9 IO43 from the UNDPIWotid Bank/WHO/Special Programme for Research and Training in Tropical Diseases (TDR) and from the MacArthur Foundation program on the Molecular Biology of Parasite Vectors. We thank Robert B. Tesh and Richard D. Ward and three anonymous reviewerj for their comments on an earlier version of this paper.