Glutamate in the immune system: Glutamate receptors in immune cells, potent effects, endogenous production and involvement in disease

Yonatan Ganor*, Mia Levite

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

29 Scopus citations

Abstract

Glutamate, an amino acid, is the principal excitatory neurotransmitter within the vertebrate nervous system. Glutamate is involved in most aspects of normal brain function including cognition, memory and learning, and also plays major roles in the development of the central nervous system, including synapse induction and elimination, and cell migration, differentiation and death. Glutamate further plays a signaling role in peripheral organs and tissues, such as the heart, kidney, intestine, lungs, muscles, liver, ovary, testis, bone, pancreas and the adrenal, pituitary and pineal glands.

Original languageEnglish
Title of host publicationNerve-Driven Immunity
Subtitle of host publicationNeurotransmitters and Neuropeptides in the Immune System
PublisherSpringer-Verlag Wien
Pages121-162
Number of pages42
ISBN (Electronic)9783709108888
ISBN (Print)9783709108871
DOIs
StatePublished - 1 Jan 2012
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2012 Springer-Verlag/Wien.

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