Abstract
Specific mutations in the human gene encoding lamin A or in the lamin A-processing enzyme, Zmpste24, cause premature aging. New data on mice and humans suggest that these mutations affect adult stem cells by interfering with the Notch and Wnt signaling pathways.
| Original language | American English |
|---|---|
| Pages (from-to) | 9-13 |
| Number of pages | 5 |
| Journal | Journal of Cell Biology |
| Volume | 181 |
| Issue number | 1 |
| DOIs |
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| State | Published - 7 Apr 2008 |