Abstract
Specific mutations in the human gene encoding lamin A or in the lamin A-processing enzyme, Zmpste24, cause premature aging. New data on mice and humans suggest that these mutations affect adult stem cells by interfering with the Notch and Wnt signaling pathways.
Original language | American English |
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Pages (from-to) | 9-13 |
Number of pages | 5 |
Journal | Journal of Cell Biology |
Volume | 181 |
Issue number | 1 |
DOIs |
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State | Published - 7 Apr 2008 |