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Gone with the Wnt/Notch: Stem cells in laminopathies, progeria, and aging

Research output: Contribution to journalComment/debate

63 Scopus citations

Abstract

Specific mutations in the human gene encoding lamin A or in the lamin A-processing enzyme, Zmpste24, cause premature aging. New data on mice and humans suggest that these mutations affect adult stem cells by interfering with the Notch and Wnt signaling pathways.

Original languageEnglish
Pages (from-to)9-13
Number of pages5
JournalJournal of Cell Biology
Volume181
Issue number1
DOIs
StatePublished - 7 Apr 2008

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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