Guidestar-free image-guided wavefront shaping

Tomer Yeminy, Ori Katz*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Optical imaging through scattering media is a fundamental challenge in many applications. Recently, breakthroughs such as imaging through biological tissues and looking around corners have been obtained via wavefront-shaping approaches. However, these require an implanted guidestar for determining the wavefront correction, controlled coherent illumination, and most often raster scanning of the shaped focus. Alternative novel computational approaches that exploit speckle correlations avoid guidestars and wavefront control but are limited to small two-dimensional objects contained within the "memory-effect" correlation range. Here, we present a new concept, image-guided wavefront shaping, allowing widefield noninvasive, guidestar-free, incoherent imaging through highly scattering layers, without illumination control. The wavefront correction is found even for objects that are larger than the memory-effect range, by blindly optimizing image quality metrics. We demonstrate imaging of extended objects through highly scattering layers and multicore fibers, paving the way for noninvasive imaging in various applications, from microscopy to endoscopy.

Original languageAmerican English
Article numbereabf5364
JournalScience advances
Issue number21
StatePublished - May 2021

Bibliographical note

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© 2021 American Association for the Advancement of Science. All rights reserved.


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