Haloperidol-induced plasma prolactin release: Sensitivity, reliability, and comparison to haloperidol antagonism of dopamine agonist-induced stereotyped behavior in the rat

J. J. Feigenbaum*, B. H. Moon, R. Catterton, J. Yanai, H. L. Klawans

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

The effects of a known antipsychotic agent (haloperidol) were assessed using both a behavioral model and a prolactin (PRL) model for screening potential antipsychotic drugs in the rat. The PRL model was found to be highly reliable and more sensitive than the behavioral model.

Original languageEnglish
Pages (from-to)383-384
Number of pages2
JournalPsychopharmacology
Volume78
Issue number4
DOIs
StatePublished - Dec 1982

Keywords

  • Apomorphine
  • Haloperidol
  • Plasma prolactin
  • Screening model
  • Stereotypy

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