Haploid Human Embryonic Stem Cells: Half the Genome, Double the Value

Atilgan Yilmaz; Mordecai Peretz; Ido Sagi; Nissim Benvenisty

doi:10.1016/j.stem.2016.10.009

Haploid Human Embryonic Stem Cells: Half the Genome, Double the Value

Atilgan Yilmaz, Mordecai Peretz, Ido Sagi^*, Nissim Benvenisty

^*Corresponding author for this work

Department of Genetics

Research output: Contribution to journal › Comment/debate

25 Scopus citations

Abstract

Recent advances in the generation of haploid embryonic stem cells (ESCs), capable of self-renewal and differentiation, have laid the groundwork for numerous biomedical applications in developmental biology and reproductive medicine. When combined with the power of genetic screening, haploid human ESCs could advance cancer research, regenerative medicine, and disease modeling.

Original language	American English
Pages (from-to)	569-572
Number of pages	4
Journal	Cell Stem Cell
Volume	19
Issue number	5
DOIs	https://doi.org/10.1016/j.stem.2016.10.009
State	Published - 3 Nov 2016

Bibliographical note

Funding Information:
A.Y. is supported by the Lady Davis Postdoctoral Fellowship , I.S. is supported by the Adams Fellowship Program of the Israel Academy of Sciences and Humanities , and N.B. is the Herbert Cohn Chair in Cancer Research . This work was partially supported by The Azrieli Foundation .

Publisher Copyright:
© 2016 Elsevier Inc.

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10.1016/j.stem.2016.10.009

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abstract = "Recent advances in the generation of haploid embryonic stem cells (ESCs), capable of self-renewal and differentiation, have laid the groundwork for numerous biomedical applications in developmental biology and reproductive medicine. When combined with the power of genetic screening, haploid human ESCs could advance cancer research, regenerative medicine, and disease modeling.",

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AU - Sagi, Ido

AU - Benvenisty, Nissim

N1 - Funding Information: A.Y. is supported by the Lady Davis Postdoctoral Fellowship , I.S. is supported by the Adams Fellowship Program of the Israel Academy of Sciences and Humanities , and N.B. is the Herbert Cohn Chair in Cancer Research . This work was partially supported by The Azrieli Foundation . Publisher Copyright: © 2016 Elsevier Inc.

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AB - Recent advances in the generation of haploid embryonic stem cells (ESCs), capable of self-renewal and differentiation, have laid the groundwork for numerous biomedical applications in developmental biology and reproductive medicine. When combined with the power of genetic screening, haploid human ESCs could advance cancer research, regenerative medicine, and disease modeling.

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Haploid Human Embryonic Stem Cells: Half the Genome, Double the Value

Abstract

Bibliographical note

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