Heat-induced changes in the rat parotid gland

Michal Horowitz; G. Mittelman; Y. Oron

doi:10.1016/0003-9969(83)90059-6

Heat-induced changes in the rat parotid gland

Michal Horowitz^*
, G. Mittelman
, Y. Oron

^*Corresponding author for this work

Institute of Biomedical Research at the Faculty of Dental Medicine

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Gland size, amylase activity, total proteins and DNA concentrations were measured in parotid gland during chronic heat exposure (34 °C). Subcellular fractionation was performed. Exposure to heat resulted in a decrease in gland size and in DNA concentration; amylase activity/100 mg tissue and amylase specific activity to protein concentration ratio increased. Subcellular fractions, except plasma membrane, decreased significantly. Thus, chronic heat exposure slows down the production of gland constituent proteins, whereas acinar function, e.g. the production and storage of exportable proteins, is not disturbed. The reduced gland size is apparently due to hypoplasia.

Original language	English
Pages (from-to)	1037-1041
Number of pages	5
Journal	Archives of Oral Biology
Volume	28
Issue number	11
DOIs	https://doi.org/10.1016/0003-9969(83)90059-6
State	Published - 1983

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title = "Heat-induced changes in the rat parotid gland",

abstract = "Gland size, amylase activity, total proteins and DNA concentrations were measured in parotid gland during chronic heat exposure (34 °C). Subcellular fractionation was performed. Exposure to heat resulted in a decrease in gland size and in DNA concentration; amylase activity/100 mg tissue and amylase specific activity to protein concentration ratio increased. Subcellular fractions, except plasma membrane, decreased significantly. Thus, chronic heat exposure slows down the production of gland constituent proteins, whereas acinar function, e.g. the production and storage of exportable proteins, is not disturbed. The reduced gland size is apparently due to hypoplasia.",

author = "Michal Horowitz and G. Mittelman and Y. Oron",

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AB - Gland size, amylase activity, total proteins and DNA concentrations were measured in parotid gland during chronic heat exposure (34 °C). Subcellular fractionation was performed. Exposure to heat resulted in a decrease in gland size and in DNA concentration; amylase activity/100 mg tissue and amylase specific activity to protein concentration ratio increased. Subcellular fractions, except plasma membrane, decreased significantly. Thus, chronic heat exposure slows down the production of gland constituent proteins, whereas acinar function, e.g. the production and storage of exportable proteins, is not disturbed. The reduced gland size is apparently due to hypoplasia.

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Heat-induced changes in the rat parotid gland

Abstract

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