Heavy metal resistance in halophilic Bacteria and Archaea

Doriana Mădălina Voica, Laszlo Bartha, Horia Leonard Banciu*, Aharon Oren

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

103 Scopus citations


Heavy metals are dense chemicals with dual biological role as micronutrients and intoxicants. A few hypersaline environmental systems are naturally enriched with heavy metals, while most metal-contaminated sites are a consequence of human activities. Numerous halotolerant and moderately halophilic Bacteria possess metal tolerance, whereas a few archaeal counterparts share similar features. The main mechanisms underlying heavy metal resistance in halophilic Bacteria and Archaea include extracellular metal sequestration by biopolymers, metal efflux mediated by specific transporters and enzymatic detoxification. Biotransformation of metals by halophiles has implications both for trace metal turnover in natural saline ecosystems and for development of novel bioremediation strategies.

Original languageAmerican English
Article numberfnw146
JournalFEMS Microbiology Letters
Issue number14
StatePublished - 1 Jul 2016

Bibliographical note

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  • Arsenic
  • Biotransformation
  • Haloarchaea
  • Heavy metal efflux
  • Metal bioreduction
  • Metal sequestration


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