Heme degradation in the presence of glutathione: A proposed mechanism to account for the high levels of non-heme iron found in the membranes of hemoglobinopathic red blood cells

Keyphrases

• Glutathione 100%
• Red Blood Cells 100%
• Heme 100%
• Non-heme Iron 100%
• Heme Degradation 100%
• Reactive Species 14%
• Lipids 14%
• Cell Lysis 14%
• Cell Membrane 14%
• Oxidative Stress 14%
• Erythrocytes 14%
• Catalase 14%
• Superoxide Dismutase 14%
• Hydrogen Peroxide 14%
• Iron Chelator 14%
• Reduced Glutathione 14%
• Mitochondrial GSH 14%
• Membrane-associated 14%
• Redox Cycling 14%
• Optimum pH 14%
• Erythrocyte Membrane 14%
• Monophosphate 14%
• Oxidative Conditions 14%
• Sickle Cell Disease 14%
• Hexose 14%
• Hexose Monophosphate Shunt 14%
• Abnormal Erythrocytes 14%
• Unstable Hemoglobin 14%
• Hemichrome 14%
• Red Blood Cell Ghosts 14%

Biochemistry, Genetics and Molecular Biology

• Glutathione 100%
• Hexose Monophosphate Shunt 100%
• Solution and Solubility 50%
• Erythrocyte Membrane 50%
• Cytolysis 50%
• Lipid 50%
• Cell Membrane 50%
• Superoxide Dismutase 50%
• Catalase 50%
• Oxidative Stress 50%
• Hydrogen Peroxide 50%
• Erythrocyte Ghost 50%