Highly Conductive Thin Uniform Gold-Coated DNA Nanowires

Avigail Stern, Gennady Eidelshtein, Roman Zhuravel, Gideon I. Livshits, Dvir Rotem, Alexander Kotlyar*, Danny Porath

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


Over the past decades, DNA, the carrier of genetic information, has been used by researchers as a structural template material. Watson-Crick base pairing enables the formation of complex 2D and 3D structures from DNA through self-assembly. Various methods have been developed to functionalize these structures for numerous utilities. Metallization of DNA has attracted much attention as a means of forming conductive nanostructures. Nevertheless, most of the metallized DNA wires reported so far suffer from irregularity and lack of end-to-end electrical connectivity. An effective technique for formation of thin gold-coated DNA wires that overcomes these drawbacks is developed and presented here. A conductive atomic force microscopy setup, which is suitable for measuring tens to thousands of nanometer long molecules and wires, is used to characterize these DNA-based nanowires. The wires reported here are the narrowest gold-coated DNA wires that display long-range conductivity. The measurements presented show that the conductivity is limited by defects, and that thicker gold coating reduces the number of defects and increases the conductive length. This preparation method enables the formation of molecular wires with dimensions and uniformity that are much more suitable for DNA-based molecular electronics.

Original languageAmerican English
Article number1800433
JournalAdvanced Materials
Issue number26
StatePublished - 27 Jun 2018

Bibliographical note

Publisher Copyright:
© 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim


  • charge transport
  • conductive atomic force microscopy
  • gold
  • metallized DNA


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