Highly fluorescent ethyl cellulose nanoparticles containing embedded semiconductor nanocrystals

Alla N. Generalova*, Svetlana V. Sizova, Vladimir A. Oleinikov, Vitaly P. Zubov, Michail V. Artemyev, Liat Spernath, Alexander Kamyshny, Shlomo Magdassi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

Highly luminescent organic nanoparticles were formed by embedding hydrophobic and hydrophilic (CdSe)ZnS quantum dots with core/shell structure into ethyl cellulose nanoparticles. The nanoparticles were prepared from oil-in-water nanoemulsions by a phase inversion process at constant temperature, followed by a solvent evaporation. The obtained fluorescent ethyl cellulose nanoparticles were functionalized by immobilization of a specific antibody, and applied in rapid agglutination test for detection of Yersinia pestis F1-antigen.

Original languageAmerican English
Pages (from-to)59-64
Number of pages6
JournalColloids and Surfaces A: Physicochemical and Engineering Aspects
Volume342
Issue number1-3
DOIs
StatePublished - 15 Jun 2009

Bibliographical note

Funding Information:
The work was financially supported by the EU Sixth frame Work Program ( “ Novel and Improved Nanomaterials, Chemistries and Apparatus for Nano-Biotechnology” NACBO, project 500804-2), by the Russian Foundation for Basic Research (Projects 07-04-01421 a, 07-04-12081 obi). In addition, the authors want to thank Prof. Sveshnikov P.G., RCMDT, Moscow, for generous supply of pair antigen–antibody which were used in this work.

Keywords

  • EIP method
  • Ethyl cellulose nanoparticles
  • Fluorescent nanoparticles
  • Nanoemulsions
  • Particle agglutination
  • Quantum dots
  • Semiconductor nanocrystals

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