TY - JOUR
T1 - How the kinetic parameters of the simple carrier are affected by an applied voltage
AU - Stein, W. D.
PY - 1977/6/16
Y1 - 1977/6/16
N2 - The kinetic parameters (K, Roo, R12, R21, and Ree) of the simple carrier model are analysed as a function of applied voltage for various cases of charged substrates and carriers. If certain parameters are invariant with voltage, strong conclusions can be made as to the charge on the free carrier. In one particular case (where the parameter R00 is invariant while R12 and R21 display a nonlinear dependence on the exponential of the voltage) it may be possible to identify the isomerisation of the carrier-substrate complex.
AB - The kinetic parameters (K, Roo, R12, R21, and Ree) of the simple carrier model are analysed as a function of applied voltage for various cases of charged substrates and carriers. If certain parameters are invariant with voltage, strong conclusions can be made as to the charge on the free carrier. In one particular case (where the parameter R00 is invariant while R12 and R21 display a nonlinear dependence on the exponential of the voltage) it may be possible to identify the isomerisation of the carrier-substrate complex.
UR - http://www.scopus.com/inward/record.url?scp=0017641729&partnerID=8YFLogxK
U2 - 10.1016/0005-2736(77)90315-7
DO - 10.1016/0005-2736(77)90315-7
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C2 - 884078
AN - SCOPUS:0017641729
SN - 0005-2736
VL - 467
SP - 376
EP - 385
JO - Biochimica et Biophysica Acta - Biomembranes
JF - Biochimica et Biophysica Acta - Biomembranes
IS - 3
ER -