Human embryo editing against disease is unsafe and unproven — despite rosy predictions

Shai Carmi; Henry T. Greely; Kevin J. Mitchell

doi:10.1038/d41586-024-04105-7

Human embryo editing against disease is unsafe and unproven — despite rosy predictions

Shai Carmi
, Henry T. Greely
, Kevin J. Mitchell

Department of Social Medicine

Research output: Contribution to journal › Comment/debate

2 Scopus citations

Abstract

Mathematical modelling suggests that it is theoretically possible to reduce risk of common diseases using heritable genome editing. Scientists argue that the technology involves considerable risk and uncertain benefits.

Original language	English
Pages (from-to)	554-556
Number of pages	3
Journal	Nature
Volume	637
Issue number	8046
DOIs	https://doi.org/10.1038/d41586-024-04105-7
State	Published - 16 Jan 2025

Bibliographical note

Publisher Copyright:
© Springer Nature Limited 2025.

Keywords

CRISPR-Cas9 genome editing
Ethics

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10.1038/d41586-024-04105-7

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title = "Human embryo editing against disease is unsafe and unproven — despite rosy predictions",

abstract = "Mathematical modelling suggests that it is theoretically possible to reduce risk of common diseases using heritable genome editing. Scientists argue that the technology involves considerable risk and uncertain benefits.",

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AB - Mathematical modelling suggests that it is theoretically possible to reduce risk of common diseases using heritable genome editing. Scientists argue that the technology involves considerable risk and uncertain benefits.

KW - CRISPR-Cas9 genome editing

KW - Ethics

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Human embryo editing against disease is unsafe and unproven — despite rosy predictions

Abstract

Bibliographical note

Keywords

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