Hybridization analysis of the methylated bases of Escherichia coli DNA

Adinah Quint; Howard Cedar

doi:10.1016/0005-2787(80)90048-9

Hybridization analysis of the methylated bases of Escherichia coli DNA

Adinah Quint^*, Howard Cedar

^*Corresponding author for this work

Institute for Medical Research Israel-Canada (IMRIC)

Research output: Contribution to journal › Article › peer-review

Abstract

The 5-methylcytosine residues of Escherichia coli DNA are randomly dispersed along the genome. Hybridization data indicate that these methyl moieties are transcribed at the same frequency as the total DNA. These results suggest that DNA methylation probably does not play a role in gene expression in bacteria.

Original language	English
Pages (from-to)	387-389
Number of pages	3
Journal	BBA Section Nucleic Acids And Protein Synthesis
Volume	606
Issue number	2
DOIs	https://doi.org/10.1016/0005-2787(80)90048-9
State	Published - 29 Feb 1980

Keywords

(E. coli)
5-Methylcytosine
DNA methylation
Gene expression
Hybridization

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10.1016/0005-2787(80)90048-9

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abstract = "The 5-methylcytosine residues of Escherichia coli DNA are randomly dispersed along the genome. Hybridization data indicate that these methyl moieties are transcribed at the same frequency as the total DNA. These results suggest that DNA methylation probably does not play a role in gene expression in bacteria.",

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Hybridization analysis of the methylated bases of Escherichia coli DNA

Abstract

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