Hypocholesterolemic effects of nutraceuticals produced from the red microalga Porphyridium sp in rats

Irit Dvir; Aliza Hannah Stark; Reuven Chayoth; Zecharia Madar; Shoshana Malis Arad

doi:10.3390/nu1020156

Hypocholesterolemic effects of nutraceuticals produced from the red microalga Porphyridium sp in rats

Irit Dvir^*, Aliza Hannah Stark, Reuven Chayoth, Zecharia Madar, Shoshana Malis Arad

^*Corresponding author for this work

Institute of Biochemistry, Food Science and Nutrition

Research output: Contribution to journal › Article › peer-review

94 Scopus citations

Abstract

Red microalgae contain functional sulfated polysaccharides (containing dietary fibers), polyunsaturated fatty acids, zeaxanthin, vitamins, minerals, and proteins. Studies in rat models support the therapeutic properties of algal biomass and isolated polysaccharides. Algal products incorporated into rat diets were found to significantly improve total serum cholesterol, serum triglycerides, hepatic cholesterol levels, HDL/LDL ratios and increased fecal excretion of neutral sterols and bile acids. Morphological and metabolic changes were induced by consumption of algal products. These results suggest that red microalgae can be used as potent hypocholesterolemic agents, and they support the potential use of red microalgae as novel nutraceuticals.

Original language	English
Pages (from-to)	156-167
Number of pages	12
Journal	Nutrients
Volume	1
Issue number	2
DOIs	https://doi.org/10.3390/nu1020156
State	Published - Dec 2009

Keywords

Dietary fiber
Foodomics
Hypocholesterolemic agents
Nutraceuticals
Red microalgae

Access to Document

10.3390/nu1020156

Cite this

@article{6da8a2bb733f4ea0bd3212de4a678285,

title = "Hypocholesterolemic effects of nutraceuticals produced from the red microalga Porphyridium sp in rats",

abstract = "Red microalgae contain functional sulfated polysaccharides (containing dietary fibers), polyunsaturated fatty acids, zeaxanthin, vitamins, minerals, and proteins. Studies in rat models support the therapeutic properties of algal biomass and isolated polysaccharides. Algal products incorporated into rat diets were found to significantly improve total serum cholesterol, serum triglycerides, hepatic cholesterol levels, HDL/LDL ratios and increased fecal excretion of neutral sterols and bile acids. Morphological and metabolic changes were induced by consumption of algal products. These results suggest that red microalgae can be used as potent hypocholesterolemic agents, and they support the potential use of red microalgae as novel nutraceuticals.",

keywords = "Dietary fiber, Foodomics, Hypocholesterolemic agents, Nutraceuticals, Red microalgae",

author = "Irit Dvir and Stark, {Aliza Hannah} and Reuven Chayoth and Zecharia Madar and Arad, {Shoshana Malis}",

year = "2009",

month = dec,

doi = "10.3390/nu1020156",

language = "אנגלית",

volume = "1",

pages = "156--167",

journal = "Nutrients",

issn = "2072-6643",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "2",

}

TY - JOUR

T1 - Hypocholesterolemic effects of nutraceuticals produced from the red microalga Porphyridium sp in rats

AU - Dvir, Irit

AU - Stark, Aliza Hannah

AU - Chayoth, Reuven

AU - Madar, Zecharia

AU - Arad, Shoshana Malis

PY - 2009/12

Y1 - 2009/12

N2 - Red microalgae contain functional sulfated polysaccharides (containing dietary fibers), polyunsaturated fatty acids, zeaxanthin, vitamins, minerals, and proteins. Studies in rat models support the therapeutic properties of algal biomass and isolated polysaccharides. Algal products incorporated into rat diets were found to significantly improve total serum cholesterol, serum triglycerides, hepatic cholesterol levels, HDL/LDL ratios and increased fecal excretion of neutral sterols and bile acids. Morphological and metabolic changes were induced by consumption of algal products. These results suggest that red microalgae can be used as potent hypocholesterolemic agents, and they support the potential use of red microalgae as novel nutraceuticals.

AB - Red microalgae contain functional sulfated polysaccharides (containing dietary fibers), polyunsaturated fatty acids, zeaxanthin, vitamins, minerals, and proteins. Studies in rat models support the therapeutic properties of algal biomass and isolated polysaccharides. Algal products incorporated into rat diets were found to significantly improve total serum cholesterol, serum triglycerides, hepatic cholesterol levels, HDL/LDL ratios and increased fecal excretion of neutral sterols and bile acids. Morphological and metabolic changes were induced by consumption of algal products. These results suggest that red microalgae can be used as potent hypocholesterolemic agents, and they support the potential use of red microalgae as novel nutraceuticals.

KW - Dietary fiber

KW - Foodomics

KW - Hypocholesterolemic agents

KW - Nutraceuticals

KW - Red microalgae

UR - http://www.scopus.com/inward/record.url?scp=77953363294&partnerID=8YFLogxK

U2 - 10.3390/nu1020156

DO - 10.3390/nu1020156

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 22253975

AN - SCOPUS:77953363294

SN - 2072-6643

VL - 1

SP - 156

EP - 167

JO - Nutrients

JF - Nutrients

IS - 2

ER -

Hypocholesterolemic effects of nutraceuticals produced from the red microalga Porphyridium sp in rats

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this