Hypocholesterolemic effects of nutraceuticals produced from the red microalga Porphyridium sp in rats

Irit Dvir*, Aliza Hannah Stark, Reuven Chayoth, Zecharia Madar, Shoshana Malis Arad

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

91 Scopus citations

Abstract

Red microalgae contain functional sulfated polysaccharides (containing dietary fibers), polyunsaturated fatty acids, zeaxanthin, vitamins, minerals, and proteins. Studies in rat models support the therapeutic properties of algal biomass and isolated polysaccharides. Algal products incorporated into rat diets were found to significantly improve total serum cholesterol, serum triglycerides, hepatic cholesterol levels, HDL/LDL ratios and increased fecal excretion of neutral sterols and bile acids. Morphological and metabolic changes were induced by consumption of algal products. These results suggest that red microalgae can be used as potent hypocholesterolemic agents, and they support the potential use of red microalgae as novel nutraceuticals.

Original languageAmerican English
Pages (from-to)156-167
Number of pages12
JournalNutrients
Volume1
Issue number2
DOIs
StatePublished - Dec 2009

Keywords

  • Dietary fiber
  • Foodomics
  • Hypocholesterolemic agents
  • Nutraceuticals
  • Red microalgae

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