TY - JOUR
T1 - Identification of the eight-membered heterocycles hicksoanes A-C from the gorgonian Subergorgia hicksoni
AU - Řezanka, Tomáš
AU - Hanuš, Lumír O.
AU - Dembitsky, Valery M.
AU - Sigler, Karel
PY - 2008/3
Y1 - 2008/3
N2 - Novel eight-membered heterocycles, named hicksoanes A-C, were isolated from the gorgonian Subergorgia hicksoni. Their structures, including the absolute configuration of all three stereocenters, were determined by means of extensive spectroscopic data. Hicksoanes have a unique structure containing a triazocane cycle, which is substituted by isoleucine and tryptophan moieties. Hicksoanes A-C showed antifeeding activity against goldfish at natural concentration (≈10 μg mL-1).
AB - Novel eight-membered heterocycles, named hicksoanes A-C, were isolated from the gorgonian Subergorgia hicksoni. Their structures, including the absolute configuration of all three stereocenters, were determined by means of extensive spectroscopic data. Hicksoanes have a unique structure containing a triazocane cycle, which is substituted by isoleucine and tryptophan moieties. Hicksoanes A-C showed antifeeding activity against goldfish at natural concentration (≈10 μg mL-1).
KW - Gorgonians
KW - Hicksoanes A-C
KW - Natural products
KW - Nitrogen heterocycles
UR - http://www.scopus.com/inward/record.url?scp=53849086514&partnerID=8YFLogxK
U2 - 10.1002/ejoc.200700645
DO - 10.1002/ejoc.200700645
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AN - SCOPUS:53849086514
SN - 1434-193X
SP - 1265
EP - 1270
JO - European Journal of Organic Chemistry
JF - European Journal of Organic Chemistry
IS - 7
ER -