Image-guided cutting-edge-needle biopsy of peripheral lymph nodes and superficial masses for the diagnosis of lymphoma

Miriam Sklair-Levy*, Gail Amir, Galia Spectre, Pinhas Lebensart, Yakov Applbaum, Ronit Agid, Sivan Lieberman, Dina Ben-Yehuda, Yoav Sherman, Engine Libson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

36 Scopus citations

Abstract

Objective: To evaluate the diagnostic efficacy of image-guided cutting-edge-needle biopsy of peripheral lymph nodes and superficial masses for the diagnosis of lymphoma, for which many still advocate open surgical resection. Methods: A retrospective analysis was performed of the medical records of 114 lymphoma patients who presented with peripheral lymphadenopathy and superficial masses and who underwent diagnostic image-guided biopsy. There were 69 non-Hodgkin lymphoma patients, 38 Hodgkin lymphoma patients, and 7 patients who were evaluated for histologic transformation of CLL or high grade lymphoma. Results: Image-guided needle biopsy was diagnostic in 96/114 (84.2%) patients. The procedure was diagnostic in 59/69 (85.5%) of NHL patients and in 30/38 of Hodgkin disease patients (79%). Diagnoses were achieved for all 7 cases where histologic transformation was suspected. Conclusion: Percutaneous image-guided needle biopsy is a safe and reliable procedure with a high diagnostic yield. It can be used as a first step in patients suspected of having lymphoma presenting with enlarged peripheral lymph nodes and superficial masses.

Original languageAmerican English
Pages (from-to)369-372
Number of pages4
JournalJournal of Computer Assisted Tomography
Volume29
Issue number3
DOIs
StatePublished - 2005
Externally publishedYes

Keywords

  • CT
  • Lymphoma
  • Percutaneous cutting-edge-needle biopsy
  • Peripheral lymph nodes
  • US

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