Imaging the neocortex functional architecture using multiple intrinsic signals: Implications for hemodynamic-based functional imaging

Amiram Grinvald, Dahlia Sharon, David Omer, Ivo Vanzetta

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Optical imaging based on intrinsic signals has provided a new level of understanding of the principles underlying cortical development, organization, and function, providing a spatial resolution of up to 20 μm for mapping cortical columns in vivo. This introduction briefly reviews the development of this technique, the types of applications that have been pursued, and the general implications of some findings for other neuroimaging techniques based on hemodynamic responses (e.g., functional magnetic resonance imaging).

Original languageAmerican English
Pages (from-to)234-250
Number of pages17
JournalCold Spring Harbor Protocols
Volume2016
Issue number3
DOIs
StatePublished - Mar 2016

Bibliographical note

Publisher Copyright:
© 2016 Cold Spring Harbor Laboratory Press.

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