Immobilized random peptide mixtures exhibit broad antimicrobial activity with high selectivity

Hadar Cheriker, Tal Stern Bauer, Yuval Oren, Shlomo Nir, Zvi Hayouka*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

In the current study, we evaluated the antimicrobial activity of randomly-sequenced peptide mixtures (RPMs) bearing hydrophobic and cationic residues that were immobilized on beads. We showed that these beads exhibit high and broad bactericidal activity against various pathogenic bacteria while possessing minimal hemolytic activity.

Original languageAmerican English
Pages (from-to)11022-11025
Number of pages4
JournalChemical Communications
Volume56
Issue number75
DOIs
StatePublished - 25 Sep 2020

Bibliographical note

Publisher Copyright:
© The Royal Society of Chemistry 2020.

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