Immune response of guinea pig lymphoid cells in vitro. III. Induction by Concanavalin A of a secondary anti-TNP response in primed guinea pig cells

J. Kettman; S. Ben-Sasson

doi:10.1016/0008-8749(80)90021-0

Immune response of guinea pig lymphoid cells in vitro. III. Induction by Concanavalin A of a secondary anti-TNP response in primed guinea pig cells

J. Kettman^*, S. Ben-Sasson

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Spleen and lymph node cells of 2,4,6-trinitrophenyl-ovalbumin (TNP-OVA)-primed guinea pigs, show a secondary anti-TNP plaque-forming cell (PFC) response on culture with Concanavalin A which does not require the addition of TNP-OVA but this response may be modestly stimulated by soluble TNP-OVA. If TNP sheep red blood cells (SRBC) are added instead as antigen, the spontaneous anti-TNP response is suppressed but an anti-SRBC response is induced.

Original language	English
Pages (from-to)	216-223
Number of pages	8
Journal	Cellular Immunology
Volume	50
Issue number	1
DOIs	https://doi.org/10.1016/0008-8749(80)90021-0
State	Published - 1 Mar 1980
Externally published	Yes

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Immune response of guinea pig lymphoid cells in vitro. III. Induction by Concanavalin A of a secondary anti-TNP response in primed guinea pig cells

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