Impact of comorbidity on well being in hypertension: Case control study

A. Lahad, Y. Yodfat*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


The impact of hypertension and comorbidity on reporting of well-being was compared in hypertensives (n = 45) and normotensives (n = 45) matched for age, sex and ethnic origin. Self-reported health, measured by the Duke profile, was worse for most measures for the hypertensive group. The mean DUSIO (Duke Severity of Illness Scale) severity of illness score, the physicians' assessment of the subjects health, was significantly higher in hypertensives than in normotensives (40.8 vs. 29.1, P=0.04). Approximately 20% of the variance in well-being scores could be explained by comorbidity. Hypertension per se explained only 2% of the variance and its correlation with well-being was not statistically significant. Perception of health (a subscale of the DUKE) was somewhat more dependent on existence of hypertension. In this study, self-assessment of health and wellbeing are explained to a large extent by differences in comorbid conditions. Well-being is independent of hypertension. These findings underscore the importance of defining and ameliorating co-existing disease in patients with hypertension.

Original languageAmerican English
Pages (from-to)611-614
Number of pages4
JournalJournal of Human Hypertension
Issue number6
StatePublished - 1993


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