Abstract
Implantable medical devices remain as one of the major research areas because of their potential applications in health care. The targeted, controlled delivery of a drug by an implantable device is an optimum therapy to treat a range of conditions. For example, coronary stenting presents both the need and the opportunity for local drug delivery. Various classes of implantable devices are listed in this chapter. This chapter focuses on requirements of implantable devices such as mechanical properties which are essential for structural support, types and prevention methods of corrosion, biocompatibility of devices and sterilisation to prevent implant associated infections. Properties of metallic, ceramic and polymeric biomaterials used in the manufacturing of implantable devices are also emphasised. Drug delivery applications of cardiovascular and orthopaedic implantable devices are discussed in detail.
Original language | American English |
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Title of host publication | Focal Controlled Drug Delivery |
Editors | Abraham J. Domb, Wahid Khan |
Place of Publication | Boston, MA |
Publisher | Springer US; Imprint: Springer |
Pages | 33-59 |
Number of pages | 27 |
ISBN (Print) | 978-1-4614-9434-8 |
DOIs | |
State | Published - 2014 |