Improved intestinal cannula for drug delivery studies in the dog

Abraham Rubinstein, Vincent Hon Kin Li, Peter Gruber, Paul Bass, Joseph R. Robinson*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

A modified light-weight intestinal cannula, based on the modified Thomas type (Thomas, 1941; Jones et al., 1971) was fabricated and tested. The design extends the useful life of the cannula and expands the versatility of the canine gastroin-testinal (Gl) system for pharmaceutical and physiological research. The cannula permits easy administration of pharmaceutical dosage forms directly into or access to ingested substances anywhere along the small intestine.

Original languageEnglish
Pages (from-to)213-217
Number of pages5
JournalJournal of Pharmacological Methods
Volume19
Issue number3
DOIs
StatePublished - May 1988
Externally publishedYes

Keywords

  • Dog
  • Drug delivery evaluation
  • Duodenal/ileal administrations
  • Intestinal cannula

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