@inproceedings{8c7537791f45473baa3384efb982adad,
title = "Improved neuronal adhesion to the surface of electronic device by engulfment of protruding micro-nails fabricated on the chip surface",
abstract = "One of the major problems in assembling efficient neuro-electronic hybrids systems is the low electrical coupling between the components. This is mainly due to the low resistance, extracellular cleft formed between the cell's plasma membrane and the substrate to which it adhere. This cleft shunts the current generated by the neuron, or the device and thus reduces the signal to noise ratio. To increase the clefts electrical resistance we fabricated gold micronails that protrude from the transistor gate surface. The micronails were functionalized by phagocytosis facilitating peptides. Cultured neurons readily engulf the functionalized micronails forming tight physical contact between the cells and the surface of the device.",
keywords = "Adhesion to substrate, Cultured neurons, Neuro-electronic hybrids, Seal resistance",
author = "Spira, {Micha E.} and Dotan Kamber and Ada Dormann and Ariel Cohen and Carmen Bartic and Gustaf Borghs and Langedijk, {J. P.M.} and Shlomo Yitzchaik and Keren Shabthai and Josef Shappir",
year = "2007",
doi = "10.1109/SENSOR.2007.4300363",
language = "אנגלית",
isbn = "1424408423",
series = "TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems",
pages = "1247--1250",
booktitle = "TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems",
note = "4th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS '07 ; Conference date: 10-06-2007 Through 14-06-2007",
}