Mitochondria are produced from the transcription and translation of genes both in the nuclear genome and in the mitochondrial genome, termed mitobiogenesis. Measuring mitobiogenesis is useful for early toxicity screening of new drug candidates. This requires an assay that is quantitative, specific, and reproducible and is also flexible enough to be applied in a variety of cell types.
|Translated title of the contribution||In-cell ELISA: Determination of the inhibition of the mitochondrial biogenesis|
|Number of pages||2|
|State||Published - Feb 2012|