In-Cell-ELISA: Bestimmung der Inhibition der mitochondrialen Biogenese

James Murray; Daniel Schwartz; Jan Hryca

doi:10.1007/s12268-012-0145-4

In-Cell-ELISA: Bestimmung der Inhibition der mitochondrialen Biogenese

Translated title of the contribution: In-cell ELISA: Determination of the inhibition of the mitochondrial biogenesis

James Murray^*, Daniel Schwartz, Jan Hryca

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Mitochondria are produced from the transcription and translation of genes both in the nuclear genome and in the mitochondrial genome, termed mitobiogenesis. Measuring mitobiogenesis is useful for early toxicity screening of new drug candidates. This requires an assay that is quantitative, specific, and reproducible and is also flexible enough to be applied in a variety of cell types.

Translated title of the contribution	In-cell ELISA: Determination of the inhibition of the mitochondrial biogenesis
Original language	German
Pages (from-to)	60-61
Number of pages	2
Journal	BioSpektrum
Volume	18
Issue number	1
DOIs	https://doi.org/10.1007/s12268-012-0145-4
State	Published - Feb 2012
Externally published	Yes

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title = "In-Cell-ELISA: Bestimmung der Inhibition der mitochondrialen Biogenese",

abstract = "Mitochondria are produced from the transcription and translation of genes both in the nuclear genome and in the mitochondrial genome, termed mitobiogenesis. Measuring mitobiogenesis is useful for early toxicity screening of new drug candidates. This requires an assay that is quantitative, specific, and reproducible and is also flexible enough to be applied in a variety of cell types.",

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In-Cell-ELISA: Bestimmung der Inhibition der mitochondrialen Biogenese

Abstract

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