Increase in bilirubin-binding affinity of serum with age of infant

J. Kapitulnik*, Ruth Horner-Mibashan, S. H. Blondheim, N. A. Kaufmann, Alex Russell

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

The bilirubin-binding affinity of infant serum, as determined by Sephadex gel filtration, began to increase during the first week of life and continued to increase gradually until the age of 5 months, when it reached that of adult serum. This increase might be due to a transition from a fetal to an adult type of serum albumin and/or to a decrease in the concentration in serum of the substances thought to compete with bilirubin for binding to albumin.

Original languageEnglish
Pages (from-to)442-445
Number of pages4
JournalJournal of Pediatrics
Volume86
Issue number3
DOIs
StatePublished - Mar 1975

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