Increase in bilirubin-binding affinity of serum with age of infant

J. Kapitulnik; Ruth Horner-Mibashan; S. H. Blondheim; N. A. Kaufmann; Alex Russell

doi:10.1016/S0022-3476(75)80982-6

Increase in bilirubin-binding affinity of serum with age of infant

J. Kapitulnik^*
, Ruth Horner-Mibashan
, S. H. Blondheim
, N. A. Kaufmann
, Alex Russell

^*Corresponding author for this work

Institute of Biomedical Research at the Faculty of Dental Medicine

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

The bilirubin-binding affinity of infant serum, as determined by Sephadex gel filtration, began to increase during the first week of life and continued to increase gradually until the age of 5 months, when it reached that of adult serum. This increase might be due to a transition from a fetal to an adult type of serum albumin and/or to a decrease in the concentration in serum of the substances thought to compete with bilirubin for binding to albumin.

Original language	English
Pages (from-to)	442-445
Number of pages	4
Journal	Journal of Pediatrics
Volume	86
Issue number	3
DOIs	https://doi.org/10.1016/S0022-3476(75)80982-6
State	Published - Mar 1975

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abstract = "The bilirubin-binding affinity of infant serum, as determined by Sephadex gel filtration, began to increase during the first week of life and continued to increase gradually until the age of 5 months, when it reached that of adult serum. This increase might be due to a transition from a fetal to an adult type of serum albumin and/or to a decrease in the concentration in serum of the substances thought to compete with bilirubin for binding to albumin.",

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AU - Russell, Alex

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AB - The bilirubin-binding affinity of infant serum, as determined by Sephadex gel filtration, began to increase during the first week of life and continued to increase gradually until the age of 5 months, when it reached that of adult serum. This increase might be due to a transition from a fetal to an adult type of serum albumin and/or to a decrease in the concentration in serum of the substances thought to compete with bilirubin for binding to albumin.

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Increase in bilirubin-binding affinity of serum with age of infant

Abstract

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