Increasing the complexity of periodic protein nanostructures by the rolling-circle-amplified synthesis of aptamers

Zoya Cheglakov; Yossi Weizmann; Adam B. Braunschweig; Ofer I. Wilner; Itamar Willner

doi:10.1002/anie.200703688

Increasing the complexity of periodic protein nanostructures by the rolling-circle-amplified synthesis of aptamers

Zoya Cheglakov^*
, Yossi Weizmann
, Adam B. Braunschweig
, Ofer I. Wilner
, Itamar Willner

^*Corresponding author for this work

Institute of Chemistry

Research output: Contribution to journal › Article › peer-review

99 Scopus citations

Abstract

(Figure Presented) The biomachinery of rolling-circle amplification relying on protein-aptamer interactions on DNA scaffolds was used to create one-dimensional DNA-protein/DNA-protein-nanoparticle hierarchical assemblies. These conjugates can serve as further templates for the immobilization of gold nanoparticles.

Original language	English
Pages (from-to)	126-130
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	47
Issue number	1
DOIs	https://doi.org/10.1002/anie.200703688
State	Published - 2008

Keywords

Aptamers
DNA
Nanoparticles
Nanostructures
Self-assembly

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10.1002/anie.200703688

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abstract = "(Figure Presented) The biomachinery of rolling-circle amplification relying on protein-aptamer interactions on DNA scaffolds was used to create one-dimensional DNA-protein/DNA-protein-nanoparticle hierarchical assemblies. These conjugates can serve as further templates for the immobilization of gold nanoparticles.",

keywords = "Aptamers, DNA, Nanoparticles, Nanostructures, Self-assembly",

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AU - Wilner, Ofer I.

AU - Willner, Itamar

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Y1 - 2008

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AB - (Figure Presented) The biomachinery of rolling-circle amplification relying on protein-aptamer interactions on DNA scaffolds was used to create one-dimensional DNA-protein/DNA-protein-nanoparticle hierarchical assemblies. These conjugates can serve as further templates for the immobilization of gold nanoparticles.

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KW - DNA

KW - Nanoparticles

KW - Nanostructures

KW - Self-assembly

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Increasing the complexity of periodic protein nanostructures by the rolling-circle-amplified synthesis of aptamers

Abstract

Keywords

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