TY - JOUR
T1 - Influence of late-age births on maternal longevity
AU - Jaffe, Dena
AU - Kogan, Liron
AU - Manor, Orly
AU - Gielchinsky, Yuval
AU - Dior, Uri
AU - Laufer, Neri
N1 - Publisher Copyright:
© 2015 Elsevier Inc.
PY - 2015/6/1
Y1 - 2015/6/1
N2 - Purpose: To examine the association between the mother's age at last birth and maternal long-term survival. Methods: Data from three national censuses (1972, 1983, and 1995) and national birth and death records (1972-2009) were used to examine the association between age at last birth and mortality while accounting for potential confounders, such as parity. Age-adjusted mortality rates and Cox proportional hazard models were used in the analysis. Results: A total of 887 women who delivered their last child after 45years of age were identified from among 178,507 women (1,592,379 person-years). Age-adjusted mortality rates from 55years of age were highest for childless women (9.2 per 1000) and decreased linearly (. P<.001) for parous women with increased age at last birth (5.2 per 1000 for women aged ≥45years at last birth). In models adjusted for age at first birth and parity, mortality risks were lowest among parous women with late-age births (≥45years) compared with parous women with their last births before 35years of age (hazard ratio, 0.58; 95% confidence interval, 0.40-0.86). Conclusions: This study provides new empirical evidence that late-age births are associated with maternal longevity, although a direct causal relation cannot be established with the information available.
AB - Purpose: To examine the association between the mother's age at last birth and maternal long-term survival. Methods: Data from three national censuses (1972, 1983, and 1995) and national birth and death records (1972-2009) were used to examine the association between age at last birth and mortality while accounting for potential confounders, such as parity. Age-adjusted mortality rates and Cox proportional hazard models were used in the analysis. Results: A total of 887 women who delivered their last child after 45years of age were identified from among 178,507 women (1,592,379 person-years). Age-adjusted mortality rates from 55years of age were highest for childless women (9.2 per 1000) and decreased linearly (. P<.001) for parous women with increased age at last birth (5.2 per 1000 for women aged ≥45years at last birth). In models adjusted for age at first birth and parity, mortality risks were lowest among parous women with late-age births (≥45years) compared with parous women with their last births before 35years of age (hazard ratio, 0.58; 95% confidence interval, 0.40-0.86). Conclusions: This study provides new empirical evidence that late-age births are associated with maternal longevity, although a direct causal relation cannot be established with the information available.
KW - Birth
KW - Longevity
KW - Maternal
KW - Mortality
KW - Reproduction
UR - http://www.scopus.com/inward/record.url?scp=84929170592&partnerID=8YFLogxK
U2 - 10.1016/j.annepidem.2014.12.002
DO - 10.1016/j.annepidem.2014.12.002
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
C2 - 25976022
AN - SCOPUS:84929170592
SN - 1047-2797
VL - 25
SP - 387
EP - 391
JO - Annals of Epidemiology
JF - Annals of Epidemiology
IS - 6
ER -