Influence of late-age births on maternal longevity

Dena Jaffe*, Liron Kogan, Orly Manor, Yuval Gielchinsky, Uri Dior, Neri Laufer

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Purpose: To examine the association between the mother's age at last birth and maternal long-term survival. Methods: Data from three national censuses (1972, 1983, and 1995) and national birth and death records (1972-2009) were used to examine the association between age at last birth and mortality while accounting for potential confounders, such as parity. Age-adjusted mortality rates and Cox proportional hazard models were used in the analysis. Results: A total of 887 women who delivered their last child after 45years of age were identified from among 178,507 women (1,592,379 person-years). Age-adjusted mortality rates from 55years of age were highest for childless women (9.2 per 1000) and decreased linearly (. P<.001) for parous women with increased age at last birth (5.2 per 1000 for women aged ≥45years at last birth). In models adjusted for age at first birth and parity, mortality risks were lowest among parous women with late-age births (≥45years) compared with parous women with their last births before 35years of age (hazard ratio, 0.58; 95% confidence interval, 0.40-0.86). Conclusions: This study provides new empirical evidence that late-age births are associated with maternal longevity, although a direct causal relation cannot be established with the information available.

Original languageEnglish
Pages (from-to)387-391
Number of pages5
JournalAnnals of Epidemiology
Volume25
Issue number6
DOIs
StatePublished - 1 Jun 2015
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2015 Elsevier Inc.

Keywords

  • Birth
  • Longevity
  • Maternal
  • Mortality
  • Reproduction

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