Infrared surface plasmon spectroscopy of living cells

V. Yashunsky*, A. Zilberstein, T. Marciano, V. Lirtsman, M. Golosovsky, D. Davidov, B. Aroeti

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review

6 Scopus citations

Abstract

We report a spectroscopic technique that combines the Fourier-Transform Infrared Spectroscopy (FTIR) with the Surface Plasmon Resonance (SPR). This FTIR-SPR technique enables sensitive infrared spectroscopy of liquid and solid objects in the attenuated total reflectance mode (ATR). The FTIR-SPR is similar to FTIR-ATR technique but has higher sensitivity due to resonance amplification of the surface electric field. FTIR-SPR is label-free method and it has unique advantages for studies of living cells. The FTIR-SPR also combines spectroscopic information inherent to FTIR with structural information provided by the Surface Plasmon Resonance (SPR). We discuss the FTIR-SPR technique for label-free studies of cell attachment to the substrate and for surface plasmon spectroscopy.

Original languageAmerican English
Pages (from-to)1617-1621
Number of pages5
JournalAIP Conference Proceedings
Volume1281
DOIs
StatePublished - 2010
EventInternational Conference on Numerical Analysis and Applied Mathematics 2010, ICNAAM-2010 - Rhodes, Greece
Duration: 19 Sep 201025 Sep 2010

Keywords

  • FTIR
  • SPR
  • biosensor
  • cell culture
  • infrared
  • surface plasmon

Fingerprint

Dive into the research topics of 'Infrared surface plasmon spectroscopy of living cells'. Together they form a unique fingerprint.

Cite this